Education

• Ph.D. in Medical Sciences, Faculty of Medicine, University of Toyama, Toyama, Japan
• Bachelor of Pharmaceutical Sciences, Faculty of Pharmacy, Cairo University, Cairo, Egypt

Research Interests

My research interests span a broad spectrum of neurological disorders, focusing on elucidating their biochemical underpinnings and identifying novel diagnostic and therapeutic approaches.

My research aims to:

1- Unravel the biochemical mechanisms that underlie various neurological disorders, including neurodegenerative diseases, neurodevelopmental disorders, and psychiatric conditions.

2- Explore cutting-edge techniques to accurately diagnose neurological disorders at early stages.

3- Discover potential therapeutic targets and develop innovative approaches to treat neurological disorders.

Selected Publications

1- Mostafa R Fayed, Khaled Ghandour, Ali Choucry, Kareem Abdou, Kaoru Inokuchi. Sleep transcends limited knowledge to support logical reward-related decisions in a novel task in male mice. Mol Brain 19, 6 (2026). https://doi.org/10.1186/s13041-025-01267-x

2- Alaa Anwar, Aya M Mustafa, Kareem Abdou, Mostafa A. Rabie, Riham A El-Shiekh, Ahmed M El-Dessouki. A comprehensive review on schizophrenia: epidemiology, pathogenesis, diagnosis, conventional treatments, and proposed natural compounds used for management. Naunyn-Schmiedeberg's Arch Pharmacol 398, 15231–15255 (2025). https://doi.org/10.1007/s00210-025-04351-0

3- Ahmed Z Ibrahim, Kareem Abdou, Masanori Nomoto, Kaori Yamada-Nomoto, Reiko Okubo-Suzuki, Kaoru Inokuchi. Sleep-driven prefrontal cortex coordinates temporal action and multimodal integration. Mol Brain 18, 4 (2025). https://doi.org/10.1186/s13041-025-01175-0

4- Mariam K Ahmed, Kareem Abdou, Weam W Ibrahim, Ahmed F Mohamed, Noha A El-Boghdady. Targeting endoplasmic reticulum stress and protein misfolding in schizophrenia: the emerging promise of sigma-1 receptor agonists. Psychopharmacology (2025). https://doi.org/10.1007/s00213-025-06940-6

5- Mariam K Ahmed, Kareem Abdou, Weam W Ibrahim, Ahmed F Mohamed, Noha A El-Boghdady. Sigma-1 Receptor Activation by Fluvoxamine Ameliorates ER Stress, Synaptic Dysfunction and Behavioral Deficits in a Ketamine Model of Schizophrenia. J Neuroimmune Pharmacol 20, 76 (2025). https://doi.org/10.1007/s11481-025-10231-4

 

Teaching Courses

1- Pharmacology (BSc.)

2- Pharmacogenetics (BSc.)

3- Phytotherapy (BSc.)

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all.

This person’s work contributes towards the following SDG(s):

 

Memberships

1- Japan Neuroscience Society (JNS), Japan.

2- Society For Neuroscience (SFN), USA.